As America's stock of athletic young men is depleted during World War II, a professional all-female baseball league springs up in the Midwest, funded by publicity-hungry candy maker Walter Harvey. Competitive sisters Dottie Hinson and Kit Keller spar with each other, scout Ernie Capadino and grumpy has-been coach Jimmy Dugan on their way to fame.

Tom Hanks,Geena Davis,Lori Petty,Madonna,Rosie O'Donnell,Megan Cavanagh,Tracy Reiner,Bitty Schram,Ann Cusack,Anne Ramsay,Freddie Simpson,Renée Coleman,Robin Knight,Patti Pelton,Kelli Simpkins,Neezer Tarleton,Connie Pounds-Taylor,Kathleen Marshall,Sharon Szmidt,Pauline Brailsford,David Strathairn,Garry Marshall,Jon Lovitz,Bill Pullman,Justin Scheller,Eddie Jones,Alan Wilder,Michael Haley,Don S. Davis,Janet Jones,Brenda Ferrari,Téa Leoni,Laurel Cronin,Wantland L. Sandel Jr.,Joe Krowka,Harry Shearer,Blaire Baron,Ryan Howell,Brian Boru Gleeson,David Franks,Ryan Olsen,Ellie Weingardt,Larissa Collins,Douglas Blakeslee,Joey Slotnick,Brian Flannery,Stephen Feagley,Rae Allen,Gregory Sporleder,Eddie Mekka,Stephen Mailer,Raymond L. Chapman,Joette Hodgen,Lynn Cartwright,Kathleen Butler,Eunice Anderson,Vera Johnson,Patricia Wilson,Mark Holton,Barbara Erwin,Betty Miller,Eugenia McLin,Barbara Pilavin,Marvin Einhorn,Shirley Burkovich,Dolores 'Pickles' Dries,Shelly Adlard,Vickie Buse,K.C. Carr,Julie Croteau,Tonya Gilles Koch,Kirsten Gretick,Stacey Gustaferro,Lisa Handirk,Cheryl Jones,Shelly Niemeyer,Sally Rutherford,Lita Schmitt,Amanda Walker,Brenda Watson,Clint Calvert,Del Close,Sarah Cosgrove-Gaumond,Cris Cunningham,Doug Decker,Andrea Helene,Gary Houston,David L. Lander,Kindra Marra,Megan McCarthy,Ed Quinn,Phil Russell,Keith Schrader,Ray Toler,Robin Wyatt

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